Effective Diffusion
Coefficients of Solutes through Alginate and ACA Biomatrices
|
| Solute |
Molecular Wt. (daltons) |
Dif. Coef. through Alginate (cm2/s) |
Dif. Coef. through ACA (cm2/s) |
| Vitamin B12 |
1,355 |
2.8 x 10-6 |
0.51 x 10-6 |
| Insulin |
5,800 |
4.0 x 10-7 |
0.50 x 10 -7 |
| Myoglobin |
24,600 |
6.6 x 10 -7 |
0.21 x 10 -7 |
| Albumin |
67,500 |
8.7 x 10 -8 |
0.92 x 10 -8 |
| The molecular weights and diffusion
coefficients of essential nutrients provide a measure of the permeation of each nutrient
through a biomatrix. Permeation through an ACA biomatrix was found to decrease with
increased molecular weight. |
Replacing
Cells to Fight Disease |