About the Cover Insulin injections prolong the lives of diabetics but can result in complications
associated with the kidneys, eyes, and nervous system. These complications arise because
the injections cannot reproduce the body's precise physiological monitoring and release of
the hormone. That complex task is performed in a healthy pancreas by beta cells, which are
clustered within the islets of Langerhans (human islets are shown enlarged in the photo at
the top left). Alternative treatments for type I diabetes sufferers, who are dependent on
insulin injections, have been sought for about 25 years, with encapsulation and
transplantation of islets emerging as a promising therapy. Researchers at SwRI are
developing an extremely biocompatible matrix to address a lingering problem with this
approach--the capsules' ability to protect islets from the body's immune system for
extended periods.
Replacing Cells to Fight Disease
Encapsulating and transplanting pancreatic islets of Langerhans has received much
attention as a treatment for insulin-dependent diabetics. SwRI scientists are testing a
biomatrix that may be able to extend cell viability and ward off immunorejection.
Saving Lives with SABRE
Created to cut through battlefield confusion, the Situational Awareness BEacon with Reply
system, or SABER, is being used by the military to reduce friendly fire, track troop and
asset movement, and link existing command, control, and communications systems.
Toolkit for Tomorrow's Car
Lighter, more efficient, powered by low-emissions technologies -- the car of the future is
being shaped by engineers and analysts whose tools are advanced simulation and modeling
programs.
Added Safety and Convenience for San
Antonio Motorists
Institute researchers are developing a number of innovative features to improve traffic
flow and increase traveler safety. The improvements will be implemented through the Texas
Department of Transportation TransGuide System.
