Chemical Encapsulation Techniques
Micro/Nano Encapsulation
Using the SwRI pilot plant equipment and
200-liter reactors, SwRI chemists produce microspheres and synthesize kilogram
batches of pharmaceuticals for phase one
clinical trials.
SwRI scientists have developed a novel core material for fluorescent monitoring of microcapsule oxidation.
Layer-by-layer deposition adds new properties and stability to existing shell systems.
SwRI scientists employ a number of chemical methods to develop highly stable microcapsules as small as 0.1 µm.
Chemical encapsulation techniques typically yield particle dispersions that can be used as is or post-processed by other methods, such as spinning disk, spray drying or fluid bed to produce free-flowing powders.
Chemical Encapsulation Techniques
Southwest Research Institute (SwRI) has developed and practices several chemical encapsulation techniques, including:
- Solvent evaporation
- In situ polymerization
- Interfacial polymerization
- Emulsion polymerization
- Simple and complex coacervation
- Layer-by-layer deposition
- Liposomes
Chemical Application
- Oil-in-water emulsions
- Water-in-oil emulsions
- Core-shell capsules or matrix particles
- Stable, high-solid dispersions
Chemical Encapsulation Characteristics
- Particle sizes from about 0.1 micron to 500 microns
- High payloads
- Uniform particle size distribution
- Scalability and high production capacity
- Batch production
Related Terminology
microencapsulation • nanoencapsulation • chemical encapsulation techniques • polymerization • emulsions • clinical trials • encapsulation • particle dispersions
