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Atomization

Extrusion

Nanoencapsulation

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Encapsulation Process Comparison

Encapsulation Process Applications:

Pharmaceuticals

Food & Nutraceuticals

Consumer & Diversified Products

Agricultural & Industrial

Encapsulation Release Mechanisms

Product Characterization

Microencapsulation Requirements Form

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	Vibrating nozzle systems produce microcapsules or microspheres with a very narrow size distribution.

• Stationary nozzle

• Centrifugal extrusion

• Vibrating nozzle

• Submerged nozzle

• Electrohydrodynamics

• Single or twin-screw extrusion

• Microextrusion

Extrusion processes produce matrix or core-shell morphologies, depending on nozzle configuration. Particle extrusion processes produce narrowly distributed particles. SwRI scientists have innovated particle extrusion processes to:

Stationary and submerged nozzles produce capsules of oils or aqueous fill materials using waxes or hydrophilic and lipophilic polymers. View high-speed video in Windows Media

• Produce capsules down to sub-micron sizes with small particle size variances

• Operate with complex thermal profiles

• Support production capacity

Fiber extrusion processes produce single or multiple fibers with diameters down to several hundred nanometers. SwRI personnel have devised fiber extrusion processes to produce:

• Matrix fibers

• Core-shell fibers

• Multilayer, fibrous structures

Extrusion Applications

• Narrow size distributions

• Core-shell morphologies

• Gas, liquid or solid cores

• Variable shell thickness

• Variable payload composition

  	These oil-filled microcapsules were produced with centrifugal coextrusion.

Extrusion Characteristics

• Sizes from1 micron to 10,000 microns

• Narrow size distribution

• Material versatility

• Scalability and high production capacity

• Continuous production

For more information about our micro/nano encapsulation extrusion capabilities, or how you can contract with SwRI, please fill out and submit the Microencapsulation Requirements form or contact Joseph Persyn, M.S., at jpersyn@swri.org or (210) 522-2691, or James Oxley, Ph.D., at joxley@swri.org or (210) 522-2913.

microencapsulation.swri.org

| Microencapsulation and Nanomaterials Department | Chemistry & Chemical Engineering Division | SwRI Home |

Southwest Research Institute^® (SwRI^®), headquartered in San Antonio, Texas, is a multidisciplinary, independent, nonprofit, applied engineering and physical sciences research and development organization with 12 technical divisions.

March 17, 2010