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Bone Cements Containing Magnetic Calcium Phosphate Nanoparticles

Abstract: 

A bone cement formulation comprising: (a) magnetic calcium phosphate nanoparticles present in an amount of 5.0-95 wt. % and having a largest linear dimension of 150 nm to 50 microns; (b) polymerizable acrylate monomer present in an amount of 5.0-95 wt. %; and (c) polyacrylate polymer present in an amount of 0-80 wt. % and having a largest linear dimension from 5.0 to 500 microns. Upon exposure to an alternating magnetic field the formulation is heated which results in polymerization of the acrylate monomer component. The formulation may also be polymerized via the use of chain polymerization initiators. 

Patent Number: 
9,566,216
Date Of Issue: 
02/14/2017
Inventors: 

Xingguo Cheng; Daniel P. Nicolella; Todd L. Bredbenner