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Reactivators of Organophosphorous Inhibited Acetylcholinesterase

Abstract: 

The present invention relates to organophosphate-inhibited acetylcholinesterase (AChE) reactivators with central nervous system (CNS) bioavailability and their associated methods of preparation including their use for treatment of exposure to AChE inhibitors such as an organophosphate (OP) insecticides and nerve agents.

Patent Number: 
9,162,983
Date Of Issue: 
10/20/2015
Inventors: 

William E. Bauta; William R. Cantrell Jr.; Michael W. Tidwell