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Product Characterization Methods

Go to Product Characterization Methods

HOW CAN WE HELP YOU?

We incorporate a variety of analytical and physical methods to characterize particles and encapsulated ingredients to routinely determine:

  • Particle size
  • Payload
  • Content uniformity and stability
  • Active ingredient release profiles and activity
  • Colloid stability
  • Particle stability

Particles

  • Sizing down to 3 nm
  • Powders
  • Dispersions (aqueous and organics)
  • Zeta potential

Particle Morphology

  • Atomic force
  • SEM/EDX (scanning electron microscope/energy-dispersive X-ray spectroscopy)
  • Environmental SEM/STEM [scanning electron microscope (SEM)/scanning-transmission electron microscope (STEM)]
  • Optical microscopy

Thermal Analysis

  • Differential scanning calorimetry
  • Thermal gravimetric analysis
  • Dynamic mechanical analysis

Rheology

  • Low viscosity fluids, gelation and curing profiles, reinforced solid mechanical properties
  • Large dynamic shear range, sub-ambient to >600°C temperature range
  • Multiple frequency waveform generation

Payload/Content

  • HPLC (high performance liquid chromatography)
  • IC, GC (gas chromatography), GC/MS (gas chromatography/mass spectrometry)
  • Fluorescent
  • Thermal gravimetric analysis

Release

  • Dissolution (pH, solvent)
  • Thermal
  • Pressure
  • Simulated body fluids
  • Cell culture
  • Tissue culture

Stability

  • Controlled environment such as:
    • Time
    • Temperature
    • Relative humidity
    • Ultraviolet
    • Acoustic
  • Simulated fluids
  • Thermal and pressure
  • Byproducts

Specialized

  • Biological Safety Laboratory (BSL) 2-4
  • Good Laboratory Practices (GLP)