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Composition and Method of Promoting Hard Tissue Healing

Abstract: 

Osteoprogenitor cells encapsulated in alginate and alternatively, additionally encapsulated in poly-L-lysine and/or agarose
promote regeneration of bone at the site of implantation. The present invention provides a composition comprising
osteoprogenitor cells embedded or encapsulated in alginate and the use of said microcapsules for the facilitation of bone
regeneration.

Patent Number: 
5,294,446
Date Of Issue: 
03/15/1994
Inventors: 

H.W. Schlameus;William C. Fox;Donald J. Mangold;Robert G. Triplett;George R. Holt;Thomas B. Aufdemorte