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Enhancement of Absorption of Radioprotective Drugs

Abstract: 

The present invention provides a pharmaceutical composition for enhancing gastrointestinal tract absorption of a radioprotective drug comprising a therapeutically effective dosage amount of a bioactive polar radioprotective agent, such as ethiofos, its active metabolites, and pharmaceutically acceptable salts thereof and a chelating agent selected from the group consisting of EDTA, EGTA, citrate and therapeutically acceptable salts thereof. A method for enhancing the rate of gastrointestinal absorption of radioprotective agents is also provided.

Patent Number: 
5,167,947
Date Of Issue: 
12/01/1992
Inventors: 

Richard S. Geary