The present disclosure relates to a bone fracture risk assessment method and system. The method may include generating a volumetric model corresponding to a three-dimensional image of a bone structure for each bone structure in a set of bone structures. The method may further include defining a vector of variables for each bone structure. Each variable in the vector of variables may include a three-dimensional position of one of a number of volumetric vertices and at least one parameter associated with the one volumetric vertex. The method may include generating a set of individual vectors and performing variable reduction on the set of individual vectors. The method may further include determining a discriminator based at least in part on a result of the variable reduction.
Daniel P. Nicolella; Todd L. Bredbenner