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Delivery Substrates from Aligned Polymer Biomaterials for Tissue Repair

Abstract: 

An aligned polymer article including substrates, wherein the substrates are not covalently bonded to the aligned collagen and a method of forming such articles wherein substrates are mixed with a polymer in solution to form a polymer-substrate mixture. The mixture is placed in an electrochemical cell and a voltage is applied to the cell generating a pH gradient, wherein the polymer aligns in the cell and migrates to the isoelectric plane of the polymer solution. 

Full Text:
US Patent and Trademark Office

Patent Number: 
9,770,415
Date Of Issue: 
09/26/2017
Inventors: 

Xingguo Cheng