Using a variety of methods, we can create stable taste-masked, enteric-coated and sustained-release oral formulations that conform to current Good Manufacturing Practices (cGMP) standards. Using cGMP suites, our scientists can prepare the micro- or nanoparticles for filling into hard gelatin capsules or compression into tablets.
Microencapsulated products in the pharmaceutical industry are common, particularly when sustained release of a medication is required. Aspirin provides effective relief for fever, inflammation, and arthritis, but direct doses of aspirin can cause peptic ulcers and bleeding. The drug is therefore sometimes encapsulated in ethyl cellulose or hydroxypropyl methylcellulose and starch (aspirin tablets are formed by pressing together collections of these microcapsules). Rather than being released all at once, the aspirin diffuses through the shell in a slow, sustained dose.