Composition and Method of Promoting Hard Tissue Healing

Abstract

Osteoprogenitor cells encapsulated in alginate and alternatively, additionally encapsulated in poly-L-lysine and/or agarose
promote regeneration of bone at the site of implantation. The present invention provides a composition comprising
osteoprogenitor cells embedded or encapsulated in alginate and the use of said microcapsules for the facilitation of bone
regeneration.

Patent Number
5,294,446
Date Of Issue
Inventors

H.W. Schlameus; William C. Fox; Donald J. Mangold; Robert G. Triplett; George R. Holt; Thomas B. Aufdemorte