Abstract:
This invention provides illudin derivatives, intermediates, preparation methods, pharmaceutical compositions and uses thereof. Specific examples include novel synthetic routes to prepare illudin derivatives and an illudin derivative having a positive optical rotation, which has therapeutic value.
Patent Number:
11,739,043
Date Of Issue:
08/29/2023
Inventors:
Gregory J. Tobin; Shawn T. Blumberg; Andrey D. Malakhov