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Two Phase Bioactive Formulations of Bis-Quarternary Pyridinium Oxime Sulfonate Salts

Abstract: 

The present invention relates to two phase systems of a bioactive ingredient in particle form that has limited or no solubility in a liquid medium, which provides stability to the bioactive ingredient that is similar to the bioactive ingredient when in the solid state. The bioactive ingredient may be capable of therapeutically treating for the presence of a cholinesterase inhibitor. The bio active ingredient comprises 1,1'-methlyenebis[4-[(hydroxyimino)methyl]-pyridinium]dimethane- sulfonate.

Patent Number: 
8,722,706
Date Of Issue: 
05/13/2014
Inventors: 

Hong Dixon; Joseph A. McDonough; Larry Allen Cabell; Patricia Underwood